duodenal ulcer

duodenal ulcer
an ulcer in the duodenum, caused by the action of acid and pepsin on the duodenal lining (mucosa) of a susceptible individual. It is usually associated with an increased output of stomach acid. Infection of the antrum of the stomach with Helicobacter pylori is almost always present. Symptoms include pain in the upper abdomen, especially when the stomach is empty, which often disappears completely for weeks or months; vomiting may occur. Complications include bleeding (see haematemesis), perforation, and obstruction due to scarring (see pyloric stenosis). Symptoms are relieved by antacid medicines; most ulcers heal if treated by an antisecretory drug, or if H. pylori is eradicated by a combination of a proton-pump inhibitor (or an H2-receptor antagonist) and antibiotics. Surgery (see gastrectomy, vagotomy) is now rarely required.

The new mediacal dictionary. 2014.

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  • duodenal ulcer — noun a peptic ulcer of the duodenum • Hypernyms: ↑peptic ulcer, ↑peptic ulceration * * * noun : a peptic ulcer situated in the duodenum * * * Pathol. a peptic ulcer located in the duodenum. * * * duodenal ulcer, an ulcer in the wall of the… …   Useful english dictionary

  • Duodenal ulcer — An ulcer (a hole in the lining) of the duodenum (the first portion of the small intestine). Ulcers can affect the stomach, duodenum, or esophagus. Their formation is related to H. pyloridus bacteria in the stomach, anti inflammatory medications,… …   Medical dictionary

  • duodenal ulcer — Pathol. a peptic ulcer located in the duodenum. * * * …   Universalium

  • duodenal ulcer — noun A peptic ulcer located in the duodenum …   Wiktionary

  • duodenal ulcer — sore or ulcer in the duodenum (first part of the small intestine) …   English contemporary dictionary

  • duodenal ulcer — du′ode′nal ul′cer n. pat a peptic ulcer located in the duodenum …   From formal English to slang

  • Ulcer — duodenal ulcer. Ulcers are healing wounds that develop on the skin, mucous membranes, or eye. Although they have many causes, they are marked by: # Loss of integrity of the area # Secondary infection of the site by bacteria, fungus or virus #… …   Wikipedia

  • Ulcer — An area of tissue erosion, for example, of the skin or lining of the gastrointestinal (GI) tract. Due to the erosion, an ulcer is concave. It is always depressed below the level of the surrounding tissue. Ulcers can have diverse causes. Ulcers on …   Medical dictionary

  • Ulcer, peptic — A peptic ulcer is a hole in the lining of the stomach, duodenum, or esophagus. A peptic ulcer of the stomach is called a gastric ulcer, an ulcer of the duodenum is a duodenal ulcer, and a peptic ulcer of the esophagus is an esophageal ulcer. A… …   Medical dictionary

  • ulcer — n. 1) a break in an epithelial surface. 2) a break in the skin extending to all its layers, or a break in the mucous membrane lining the alimentary tract, that fails to heal and is often accompanied by inflammation. Of the many types of skin… …   The new mediacal dictionary

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